超敏ECL发光液Enlight^TM-Plus

Int Immunopharmacol. 2024 Jan 8:128:111480.doi: 10.1016/j.intimp.2023.111480. Online ahead of print. Role of Interleukin-21 in retinal ischemia-reperfusion injury: Unveiling the impact on retinal ganglion cell apoptosis 白细胞介素-21在视网膜缺血再灌注损伤中的作用：揭示其对视网膜神经节细胞凋亡的影响

Synth Syst Biotechnol. 2023 Dec 3;9(1):1-10.doi: 10.1016/j.synbio.2023.11.010. eCollection 2024 Mar. EMT transcription factors activated circuits: A novel tool to study EMT dynamics and its therapeutic implications EMT转录因子激活回路：研究EMT动力学及其治疗意义的新工具

Autophagy. 2023 Dec 12:1-28.doi: 10.1080/15548627.2023.2293442. Online ahead of print. Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185 Senecavirus A通过RNF185催化2C蛋白与K27连接的泛素化TUFM的直接相互作用诱导线粒体自噬以促进自身复制(IF:13.391).

BMC Mol Cell Biol. 2023 Aug 7;24(1):24.doi: 10.1186/s12860-023-00487-0. BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway BMP9通过激活SDF1/CXCR4途径维持HTR-8/Svneo滋养层细胞的表型

Mol Cell Biochem. 2019 Jan;450(1-2):149-158. doi: 10.1007/s11010-018-3381-1. Epub 2018 Jun 15.（蛛网膜下腔出血后早期脑损伤中线粒体依赖性细胞凋亡）

Oncol Rep. 2018 Sep;40(3):1743-1751. doi: 10.3892/or.2018.6572. Epub 2018 Jul 13.
BMP9 inhibits the growth of breast cancer cells by downregulation of the PI3K/Akt signaling pathway.（BMP9通过下调PI3K/Akt信号通路抑制乳腺癌细胞的生长 ）

Vet Microbiol. 2018 Sep;223:134-143. doi: 10.1016/j.vetmic.2018.08.012. Epub 2018 Aug 9.
Porcine reproductive and respiratory syndrome virus nsp1β and nsp11 antagonize the antiviral activity of cholesterol-25-hydroxylase via lysosomal degradation.（猪繁殖与呼吸综合征病毒与胆固醇-25-羟化酶的抗病毒活性 ）

J Proteome Res. 2018 Sep 7;17(9):3143-3152. doi: 10.1021/acs.jproteome.8b00260. Epub 2018 Aug 21.
SIRT3 Overexpression Inhibits Growth of Kidney Tumor Cells and Enhances Mitochondrial Biogenesis.(sirt3的过度表达抑制肾肿瘤细胞的生长并增强线粒体的生物生成)

Exp Ther Med. 2017 Oct;14(4):3179-3183. doi: 10.3892/etm.2017.4857. Epub 2017 Jul 31.
Bax is involved in the anticancer activity of Velcade in colorectal cancer..（Bcl‑2相关X蛋白与结直肠癌研究）

Cell Prolif. 2017 Oct;50(5). doi: 10.1111/cpr.12366. Epub 2017 Aug 1.
Visfatin mediates doxorubicin resistance in human non-small-cell lung cancer via Akt-mediated up-regulation of ABCC1.（内脂素与人非小细胞肺癌中阿霉素耐药研究）

Exp Cell Res. 2017 Oct 1;359(1):251-256. doi: 10.1016/j.yexcr.2017.07.022. Epub 2017 Jul 19.
Adipocytes promote nicotine-induced injury of endothelial cells via the NF-κB pathway.（脂肪细胞与尼古丁介诱导的内皮细胞损伤研究）

Acta Pharm Sin B. 2017 Sep;7(5):583-592. doi: 10.1016/j.apsb.2017.04.002. Epub 2017 May 11.
Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway in mice.（华中五味子提取物与慢性及急性酒精性肝损伤研究）

Oncol Rep. 2017 Sep;38(3):1767-1773. doi: 10.3892/or.2017.5793. Epub 2017 Jul 6.
Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stress.(烟酰胺磷酸核糖转移酶与细胞生长和氧化应激敏感性研究）

J Cardiovasc Pharmacol. 2017 Sep;70(3):184-193. doi: 10.1097/FJC.0000000000000504.
Resveratrol Ameliorates Cardiac Dysfunction by Inhibiting Apoptosis via the PI3K/Akt/FoxO3a Pathway in a Rat Model of Diabetic Cardiomyopathy.（白藜芦醇与糖尿病心肌病大鼠心肌功能研究）

Oncotarget. 2017 Jul 22;8(39):65876-65888. doi: 10.18632/oncotarget.19507. eCollection 2017 Sep 12.
The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells.（基因工程药物rhCNB通过线粒体途径诱导肿瘤细胞凋亡）

Toxicology and Applied Pharmacology. 2017 June 13.
Analysis of metabonomic profiling alterations in a mouse model of colitis-associated cancer and 2-deoxy-D-glucose treatment.（结肠炎相关癌症和2-脱氧-D-葡萄糖治 疗小鼠模型的代谢组学变化分析）

Toxicol Appl Pharmacol. 2017 Jun 1;324:12-25. doi: 10.1016/j.taap.2017.03.022. Epub 2017 Mar 31.
Valproate induced hepatic steatosis by enhanced fatty acid uptake and triglyceride synthesis.（丙戊酸钠通过增强脂肪酸摄取和甘油三酯合成诱导肝脂肪变性）

Mol Med Rep. 2017 Jun;15(6):4035-4040. doi: 10.3892/mmr.2017.6523. Epub 2017 Apr 27.
Purification of a polyclonal antibody against CD147 for ELISA using antigen‑immunoaffinity chromatography.（抗原-免疫亲和层析法纯化抗CD147多克隆抗体）

Apoptosis. 2017 May;22(5):639-646. doi: 10.1007/s10495-017-1349-3.
Propofol attenuates H2O2-induced oxidative stress and apoptosis via the mitochondria- and ER-medicated pathways in neonatal rat cardiomyocytes.（大鼠心肌细胞中线粒体和ER介导的氧化应激和凋亡研究）

Carcinogenesis. 2017 Apr 1;38(4):474-483. doi: 10.1093/carcin/bgx023.
PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C.（PPARα通过新的靶基因肉碱棕榈酰转移酶1C调节肿瘤细胞增殖和衰老）

Helicobacter. 2016 Dec;21(6):554-564. doi: 10.1111/hel.12311. Epub 2016 Apr 6.
The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells.（由幽门螺杆菌引起的TRAF1上调在感染细胞中具有抗凋亡作用）

BMC Biotechnol. 2016 Sep 1;16(1):65. doi: 10.1186/s12896-016-0294-5.
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.（靶向癌细胞枯草杆菌细胞毒性评估）

Mol Med Rep. 2016 Jun;13(6):4577-84. doi: 10.3892/mmr.2016.5102. Epub 2016 Apr 11.
DNase I aggravates islet β-cell apoptosis in type 2 diabetes（DNase I 加重2型糖尿病中胰岛β-cell的凋亡）

J Proteome Res. 2016 May 6;15(5):1506-14. doi: 10.1021/acs.jproteome.5b01125. Epub 2016 Mar 24.
Silencing PRDX3 Inhibits Growth and Promotes Invasion and Extracellular Matrix Degradation in Hepatocellular Carcinoma Cells.（线粒体过氧化物还原酶PRDX3的沉默可以抑制肝癌细胞的生长并能促进肝癌细胞的侵袭和细胞外基质的降解）

Acta Biochim Biophys Sin (Shanghai). 2016 Apr;48(4):326-33. doi: 10.1093/abbs/gmw008. Epub 2016 Mar 2.
Intermolecular disulfide bond in the dimerization of S-periaxin mediated by Cys88 and Cys139.（由Cys88 和 Cys139介导的S-periaxin 蛋白二聚体中分子间的二硫键）

Sci Rep. 2016 Apr 6;6:24034. doi: 10.1038/srep24034.(IF:5.578).
Trim69 regulates zebrafish brain development by ap-1 pathway（Trim69 蛋白通过ap-1通路调节斑马鱼脑部发育）

Nat Commun. 2016 Mar 31;7:11123. doi: 10.1038/ncomms11123.(IF:11.329).Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways.（低氧微环境协同TGF-β信号以及Hippo信号在肿瘤发展中的作用）

Acta Pharmacol Sin. 2016 Mar;37(3):382-9. doi: 10.1038/aps.2015.120. Epub 2016 Jan 25.
Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway （小鼠急性肝损伤研究）

Acta Pharmacol Sin. 2016 Mar;37(3):382-9. doi: 10.1038/aps.2015.120. Epub 2016 Jan 25.
Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway （小鼠急性肝损伤研究）

J Pharmacol Sci. 2016 Feb;130(2):66-71. doi: 10.1016/j.jphs.2015.11.006. Epub 2015 Dec 12.
SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells.（孕烷X 受体的类泛素化在LS174T细胞中抑制CYP3A4和 P-gp的表达和活性）

Drug Metabolism and Disposition 2015 December 10.
Hepato-Protective Effects of Schisandra Sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Mice are Associated With the Activation of PXR Pathway and Promotion of Liver Regeneration（华中五味子提取物对石胆酸诱导的胆汁淤积小鼠的肝保护作用）

Am J Physiol Heart Circ Physiol. 2015 Oct;309(8):H1303-13. doi: 10.1152/ajpheart.00290.2015. Epub 2015 Sep 14.
MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury.(MicroRNA-141调节内皮细胞ICAM-1的表达水平以降低心肌缺血再灌注损伤）

Sci China Life Sci. 2015 Sep;58(9):867-75. doi: 10.1007/s11427-015-4915-3. Epub 2015 Sep 9.
Kv1.3 channel blockade enhances the phagocytic function of RAW264.7 macrophages. 9Kv1.3通道的阻断可以增强RAW264.7巨噬细胞的吞噬作用）

Mol Med Rep. 2015 Sep;12(3):4109-4116. doi: 10.3892/mmr.2015.3973. Epub 2015 Jun 22.
Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis.（肌球蛋白轻链激酶抑制剂ML7对动脉硬化模型小鼠的血管内皮功能障碍的提高作用）

J Zhejiang Univ Sci B. 2015 Sep;16(9):780-7. doi: 10.1631/jzus.B1500015.
Protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis.（左旋肉碱对环磷酰胺致病菌引起的生殖细胞凋亡的保护作用）

Cell Physiol Biochem. 2015;37(2):816-24. doi: 10.1159/000430398. Epub 2015 Sep 11.
Cryptotanshinone Reverses Cisplatin Resistance of Human Lung Carcinoma A549 Cells through Down-Regulating Nrf2 Pathway.( 隐丹参酮通过下调Nrf2通路逆转人肺腺癌A549细胞的顺铂耐药性）

Cell Physiol Biochem. 2015;35(2):710-21. doi: 10.1159/000369731. Epub 2015 Jan 28.
Effects of nicotinamide N-methyltransferase on PANC-1 cells proliferation, metastatic potential and survival under metabolic stress.（烟酰胺N-甲基转移酶对PANC-1细胞在代谢性应激条件下增殖、代谢转移潜能和生存力的作用研究）.

J Biol Chem. 2015 Jul 24;290(30):18865-73. doi: 10.1074/jbc.M114.635375. Epub 2015 Jun 12.
Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.（Polo样激酶1（Plk1）通过影响人端粒酶逆转录酶（hTERT）稳定性从而上调端粒酶活性）.

BMC Complement Altern Med. 2015 May 27;15:155. doi: 10.1186/s12906-015-0673-9.
Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis.（中药通过抑制炎症和细胞凋亡改善肾病）

Biomed Eng Online. 2015 Apr 15;14:33. doi: 10.1186/s12938-015-0028-2.
Porous deproteinized bovine bone scaffold with three-dimensional localized drug delivery system using chitosan microspheres.（采用壳聚糖微球的多孔牛骨支架三维局部药物输送系统）

J Virol. 2015 Mar;89(5):2739-49. doi: 10.1128/JVI.02784-14. Epub 2014 Dec 24.
Hepatitis B virus regulates apoptosis and tumorigenesis through the microRNA-15a-Smad7-transforming growth factor beta pathway.（乙型肝炎病毒通过microrna-15a-smad7转化生长因子β通路调节细胞凋亡和肿瘤发生）

Drug Metab Dispos. 2015 Mar;43(3):317-24. doi: 10.1124/dmd.114.062067. Epub 2014 Dec 22.
Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera Extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine.（华中五味子提取物对醋氨酚肝损伤的治疗效果）.

Nat Cell Biol. 2015 Jan;17(1):95-103. doi: 10.1038/ncb3073. Epub 2014 Dec 1.(IF:19.679).
Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase.（低氧通过E3泛素连接酶SIAH2调控Hippo信号通路 ）

Diabetes Res Clin Pract. 2014 Apr;104(1):136-42. doi: 10.1016/j.diabres.2014.01.014. Epub 2014 Jan 30.
The changes of neutrophil gelatinase-associated lipocalin in plasma and its expression in adipose tissue in pregnant women with gestational diabetes.血浆中性粒细胞明胶酶相关脂蛋白的变化及其意义

Chem Biol Interact. 2014 Apr 25;213:44-50. doi: 10.1016/j.cbi.2014.02.004. Epub 2014 Feb 14.
Down-regulation of P-gp expression and function after Mulberroside A treatment: Potential role of protein kinase C and NF-kappa B.多糖a治疗后p-gp表达和功能的下调

J Proteome Res. 2014 Feb 7;13(2):786-95. doi: 10.1021/pr4010597. Epub 2013 Dec 13.
Overexpression of CD38 Decreases Cellular NAD Levels and Alters the Expression of Proteins Involved in Energy Metabolism and Antioxidant Defense.cd38的过度表达降低了细胞nad水平并改变了nad的表达

Ann Hepatol. 2013 Sep-Oct;12(5):815-21.
Notch signal protects non-parenchymal cells from ischemia/reperfusion injury in vitro by repressing ROS.Notch信号对非实质细胞缺血再灌注损伤的保护作用

Pharmacology. 2013;92(3-4):121-30. doi: 10.1159/000353774. Epub 2013 Aug 31.
Effect of phorbol 12-myristate 13-acetate on function and gene expression of P-glycoprotein in adriamycin-resistant K562/ADM cells.肉豆蔻酸-13-乙酸酯对大鼠肝细胞功能及基因表达的影响

PLoS One. 2013 Aug 15;8(8):e70884. doi: 10.1371/journal.pone.0070884. eCollection 2013.
Toxoplasma gondii protein disulfide isomerase (TgPDI) is a novel vaccine candidate against toxoplasmosis.弓形虫蛋白二硫键异构酶（TgPDI）

PLoS One. 2013;8(3):e59610. doi: 10.1371/journal.pone.0059610. Epub 2013 Mar 26.
Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.氧化应激诱导单核细胞坏死

Metallomics. 2013 Jun;5(7):836-43. doi: 10.1039/c3mt20249f.
Vanadium compounds modulate PPARγ activity primarily by increasing PPARγ protein levels in mouse insulinoma NIT-1 cells.钒化合物主要通过增加pparγp来调节pparγ活性

J Med Food. 2013 Apr;16(4):280-7. doi: 10.1089/jmf.2012.2486. Epub 2013 Mar 20.
Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.

J Cell Sci. 2012 Sep 15;125(Pt 18):4219-29. doi: 10.1242/jcs.086553. Epub 2012 May 28.
Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.Bat3调节细胞凋亡增强YWK-II/APLP2蛋白的稳定性

PLoS One. 2012;7(6):e39165. doi: 10.1371/journal.pone.0039165. Epub 2012 Jun 14.
Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice.可溶性环氧化物水解酶抑制高脂饮食诱导

FEBS Lett. 2012 May 21;586(10):1497-503. doi: 10.1016/j.febslet.2012.04.005. Epub 2012 Apr 18.
Nemo-like kinase promotes etoposide-induced apoptosis of male germ cell-derived GC-1 cells in vitro.Nemo样激酶促进依托泊苷诱导雄性生殖细胞凋亡

FEBS Lett. 2011 Aug 4;585(15):2493-500. doi: 10.1016/j.febslet.2011.06.031. Epub 2011 Jul 2.
Cyclin T2: a novel miR-15a target gene involved in early spermatogenesis.研究Cylin T2在早期精子发生中的作用

Mol Biol Cell. 2010 Dec;21(24):4312-24. doi: 10.1091/mbc.E10-04-0310. Epub 2010 Oct 27.
A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis.睾丸特异性GTPase与蛋白酶体生物